166663-25-8 阿尼芬净

阿尼芬净

英文名称:anidulafungin
CAS:

166663-25-8

分子式:C58H73N7O17
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阿尼芬净简介

Anidulafungin (brand names: Eraxis (in U.S. and Russia), Ecalta (in Europe)) is a semisynthetic echinocandin used as an antifungal drug. Anidulafungin was originally manufactured and submitted for FDA approval by Vicuron Pharmaceuticals. Pfizer acquired the drug upon its acquisition of Vicuron in the fall of 2005. Pfizer gained approval by the Food and Drug Administration (FDA) on February 21, 2006; it was previously known as LY303366. Preliminary evidence indicates it has a similar safety profile to caspofungin. Anidulafungin has proven efficacy against esophageal candidiasis, but its main use will probably be in invasive Candida infection; it may also have application in treating invasive Aspergillus infection. It is a member of the class of antifungal drugs known as the echinocandins; its mechanism of action is by inhibition of (1→3)-β-D-glucan synthase, an enzyme important to the synthesis of the fungal cell wall.

阿尼芬净基本信息

中文名称 阿尼芬净 英文名称 anidulafungin
中文别名

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英文别名

V-Echinocandin; Anidulafungin; VER-002; Ecalta; Eraxis;

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CAS号 166663-25-8 分子式 C58H73N7O17
分子量 1140.24000 精确质量 1139.51000
PSA 377.42000 LOGP 0.65480

阿尼芬净编号系统

UNII 9HLM53094I

阿尼芬净物化性质

密度:
1.47g/cm3
沸点:
1477ºC at 760mmHg
闪点:
847ºC
折射率:
1.688
蒸汽压:
0mmHg at 25°C
SDS 1.0 中文 展开
SDS 1.0 英文 展开
阿尼芬净
CAS号:166663-25-8 分子式:C58H73N7O17 分子量:1140.24000

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