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69-22-7 柠檬酸咖啡因

柠檬酸咖啡因

英文名称:2-hydroxypropane-1,2,3-tricarboxylic acid,1,3,7-trimethylpurine-2,6-dione
CAS:

69-22-7

分子式:C14H18N4O9
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柠檬酸咖啡因简介

Caffeine citrate (trade name Cafcit) is a citrate salt of caffeine, sometimes used in medical treatment, including short-term treatment of apnea of prematurity (lack of breathing in premature infants). Caffeine citrate functions in much the same capacity as does caffeine, but takes effect more quickly; its speed of dissociation is faster than that of caffeine. Like its sister compound, it can be used to dispel pain from a headache. However, caffeine sodium benzoate is typically only used to treat severe migraines, not the citrate form.
The drug is prepared simply by combining anhydrous caffeine with citric acid monohydrate and sodium citrate dihydrate. In method of action, the preparation is exactly identical to that of caffeine base as the citrate counter ion dissociates in water. Doses of caffeine citrate, due to the added weight of the citrate moiety, are understandably higher than with caffeine base, i.e., it takes a larger dose to get the same amount of caffeine. The ratio of therapeutic doses of caffeine base to its citrate salt is typically 1:2. It is therefore generally recommended that caffeine is prescribed in terms of caffeine base, and not caffeine citrate.
It is on the WHO Model List of Essential Medicines, a list of the most important medication needed in a basic health system.

柠檬酸咖啡因基本信息

中文名称 柠檬酸咖啡因 英文名称 2-hydroxypropane-1,2,3-tricarboxylic acid,1,3,7-trimethylpurine-2,6-dione
中文别名

檸檬酸咖啡鹼;

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英文别名

Citrated caffein; caffeine citrate; Kaffein,Citrat; Citric acid,compd. with caffeine (1:1); Caffeine,Citrated; Caffeina citrate; Coffeinum-citrate; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, mixt. with 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione; UNII-U26EO4675Q; Caffeine citrate (1:1); 1,3,7-Trimethyl-3,7-dihydro-purin-2,6-dion; 1,3,7-trimethyl-3,7-dihydro-purine-2,6-dione;

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CAS号 69-22-7 分子式 C14H18N4O9
分子量 386.31400 精确质量 386.10700
PSA 193.95000 LOGP -2.27780

柠檬酸咖啡因编号系统

UNII U26EO4675Q

安全信息

危险品运输编码:
UN 1544
危险类别:
6.1(b)
包装等级:
III
SDS 1.0 中文 展开
SDS 1.0 英文 展开
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核磁图谱 1H NMR : Predict

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柠檬酸咖啡因
CAS号:69-22-7 分子式:C14H18N4O9 分子量:386.31400

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