| Product name | 2,2-Dibromo-2-cyanoacetamide |
|---|
| Product number | - |
|---|---|
| Other names | Dibromocyano acetic acid amide |
| Identified uses | For industry use only. Processing aids, specific to petroleum production |
|---|---|
| Uses advised against | no data available |
| Company | MOLBASE (Shanghai) Biotechnology Co., Ltd. |
|---|---|
| Address | Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road, Xuhui District, Shanghai, China |
| Telephone | +86(21)64956998 |
| Fax | +86(21)54365166 |
| Emergency phone number | +86-400-6021-666 |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
Acute toxicity - Oral, Category 3
Skin irritation, Category 2
Skin sensitization, Category 1
Serious eye damage, Category 1
Acute toxicity - Inhalation, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
2.2 GHS label elements, including precautionary statements| Pictogram(s) |    |
|---|---|
| Signal word | Danger |
| Hazard statement(s) | H301 Toxic if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H318 Causes serious eye damage H330 Fatal if inhaled H400 Very toxic to aquatic life |
| Precautionary statement(s) | |
| Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection. P273 Avoid release to the environment. |
| Response | P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor/… P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P332+P313 If skin irritation occurs: Get medical advice/attention. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P313 If skin irritation or rash occurs: Get medical advice/attention. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310 Immediately call a POISON CENTER/doctor/… P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P320 Specific treatment is urgent (see ... on this label). P391 Collect spillage. |
| Storage | P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed. |
| Disposal | P501 Dispose of contents/container to ... |
none
3.Composition/information on ingredients 3.1 Substances| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| 2,2-Dibromo-2-cyanoacetamide | 2,2-Dibromo-2-cyanoacetamide | 10222-01-2 | none | 100% |
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaledIf breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contactWash off with soap and plenty of water. Consult a physician.
In case of eye contactRinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowedNever give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms/effects, acute and delayedExcerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. (ERG, 2016)
4.3 Indication of immediate medical attention and special treatment needed, if necessary/SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Poisons A and B/
5.Fire-fighting measures 5.1 Extinguishing media Suitable extinguishing mediaExcerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: SMALL FIRE: Dry chemical, CO2 or water spray. LARGE FIRE: Dry chemical, CO2, alcohol-resistant foam or water spray. Move containers from fire area if you can do it without risk. Dike fire-control water for later disposal; do not scatter the material. FIRE INVOLVING TANKS OR CAR/TRAILER LOADS: Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. (ERG, 2016)
5.2 Specific hazards arising from the chemicalExcerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. For electric vehicles or equipment, ERG Guide 147 (lithium ion batteries) or ERG Guide 138 (sodium batteries) should also be consulted. (ERG, 2016)
5.3 Special protective actions for fire-fightersWear self-contained breathing apparatus for firefighting if necessary.
6.Accidental release measures 6.1 Personal precautions, protective equipment and emergency proceduresUse personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautionsPrevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning upPick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.
7.Handling and storage 7.1 Precautions for safe handlingAvoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilitiesStore in cool place. Keep container tightly closed in a dry and well-ventilated place.
8.Exposure controls/personal protection 8.1 Control parameters Occupational Exposure limit valuesno data available
Biological limit valuesno data available
8.2 Appropriate engineering controlsHandle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
8.3 Individual protection measures, such as personal protective equipment (PPE) Eye/face protectionSafety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protectionWear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Respiratory protectionWear dust mask when handling large quantities.
Thermal hazardsno data available
9.Physical and chemical properties| Physical state | Colorless to yellow liquid with a moldy pungent odor |
|---|---|
| Colour | White to "off white" crystalline solid |
| Odour | Mild "medicinal antiseptic" |
| Melting point/ freezing point | -65°C(lit.) |
| Boiling point or initial boiling point and boiling range | 72°C/10mmHg(lit.) |
| Flammability | no data available |
| Lower and upper explosion limit / flammability limit | no data available |
| Flash point | 74°C(lit.) |
| Auto-ignition temperature | no data available |
| Decomposition temperature | no data available |
| pH | pH at 25°C: 6.61 in 0.01% aqueous solution |
| Kinematic viscosity | no data available |
| Solubility | In water, 1.5 g/100 mL (15,000 mg/L) |
| Partition coefficient n-octanol/water (log value) | log Kow = 0.80 at pH 7; 0.795 at pH 5; 0.82 at pH 9.0 |
| Vapour pressure | 0.107mmHg at 25°C |
| Density and/or relative density | 2.451 g/cm3 |
| Relative vapour density | no data available |
| Particle characteristics | no data available |
no data available
10.2 Chemical stabilityStable under normal conditions, decomposition accelerated by light & heat.
10.3 Possibility of hazardous reactions2,2-DIBROMO-3-NITRILOPROPIONAMIDE is incompatible with bases, metals, oxidizing agents, acids. Dangerous gases may accumulate as a result of ignition and fire.
10.4 Conditions to avoidno data available
10.5 Incompatible materialsIncompatible with bases, reducing substances & nucleophiles.
10.6 Hazardous decomposition productsWhen heated to decomposition it emits very toxic fumes of Br(-) and /nitrogen oxides/.
11.Toxicological information Acute toxicity- Oral: LD50 Mammal oral 118 mg/kg
- Inhalation: LC50 Rat inhalation 0.32 mg/L/4 hr /from table/
- Dermal: no data available
no data available
Serious eye damage/irritationno data available
Respiratory or skin sensitizationno data available
Germ cell mutagenicityno data available
Carcinogenicityno data available
Reproductive toxicityno data available
STOT-single exposureno data available
STOT-repeated exposureno data available
Aspiration hazardno data available
12.Ecological information 12.1 Toxicity- Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill) juvenile; Conditions: freshwater, static; Concentration: 1300 ug/L for 96 hr (95% confidence interval: 1000-1600 ug/L) /100% purity
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water Flea) age <24 hr; Conditions: freshwater, static; Concentration: 860 ug/L for 48 hr (95% confidence interval: 560-1000 ug/L); Effect: intoxication, immobilization /100% purity
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
AEROBIC: The disappearance of 2,2-dibromo-3-nitrilopropionamide at 50 ppm in soil was more rapid than when present in an aqueous solution at a similar pH(1). Degradation in 7 soils was measured; half-lives of 4, 12, 15, 15, 6, 25, and 15 hours were reported for a sandy loam (pH 7.5), loam (pH 4.8), silty loam (pH 5.8), sandy loam (pH 6.5), loamy sand (pH 5.8), silty clay loam (pH 5.1), and loam (pH 4.8) soil, respectively(1). 2,2-Dibromo-3-nitrilopropionamide has a half-life of less than 4 hours in an aerobic aquatic metabolism study(2). Dibromoacetic acid (reached 66% of applied at 0 hour, 9% at hour 5) and 2-cyanoacetamide (reached 56.5% of applied at hour 5, 2.3% at day 30) were the major degradates(2). Other degradates include oxalic acid, bromoacetic acid, bromoacetamide, and dibromoacetonitrile(2). Oxalic acid, 2-cyanoacetamide (16% by day 2) and bromoacetamide (2% by day 2) were found in the sediment layer(2). 2,2-Dibromo-3-nitrilopropionamide, present at 100 mg/L, reached 0% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test classifying the compound as not readily biodegradable(3). Microbial degradation of 2,2-dibromo-3-nitrilopropionamide has been demonstrated by the use of tracer techniques (14C-radio-labeled) which yielded 40% 14-CO2 after two weeks in the presence of waste treatment sludge(1).
12.3 Bioaccumulative potentialAn estimated BCF of 3 was calculated in fish for 2,2-dibromo-3-nitrilopropionamide(SRC), using a log Kow of 0.80(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Using carp (Cyprinus carpio) which were exposed over an 8-week period, 2,2-dibromo-3-nitrilopropionamide was reported to have low bioconcentration (BCF value not available)(4).
12.4 Mobility in soilThe Koc of 2,2-dibromo-3-nitrilopropionamide is estimated as 58(SRC), using a log Kow of 0.80(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 2,2-dibromo-3-nitrilopropionamide is expected to have high mobility in soil.
12.5 Other adverse effectsno data available
13.Disposal considerations 13.1 Disposal methods ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packagingContainers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
14.Transport information 14.1 UN Number| ADR/RID: UN3439 | IMDG: UN3439 | IATA: UN3439 |
| ADR/RID: NITRILES, SOLID, TOXIC, N.O.S. |
| IMDG: NITRILES, SOLID, TOXIC, N.O.S. |
| IATA: NITRILES, SOLID, TOXIC, N.O.S. |
| ADR/RID: 6.1 | IMDG: 6.1 | IATA: 6.1 |
| ADR/RID: III | IMDG: III | IATA: III |
| ADR/RID: yes | IMDG: yes | IATA: yes |
no data available
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Codeno data available
15.Regulatory information 15.1 Safety, health and environmental regulations specific for the product in question| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| 2,2-Dibromo-2-cyanoacetamide | 2,2-Dibromo-2-cyanoacetamide | 10222-01-2 | none |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Not Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
| Creation Date | Aug 10, 2017 |
|---|---|
| Revision Date | Aug 10, 2017 |
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
购物车
获取报价
投诉建议
0
