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7365-45-9 4-羟乙基哌嗪乙磺酸

4-羟乙基哌嗪乙磺酸

英文名称:2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid
CAS:

7365-45-9

分子式:C8H18N2O4S
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4-羟乙基哌嗪乙磺酸简介

HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid ) is a zwitterionic organic chemical buffering agent; one of the twenty Good's buffers. HEPES is widely used in cell culture, largely because it is better at maintaining physiological pH despite changes in carbon dioxide concentration (produced by cellular respiration) when compared to bicarbonate buffers, which are also commonly used in cell culture. The dissociation of water decreases with falling temperature, but the dissociation constants (pK) of many other buffers do not change much with temperature. HEPES is like water in that its dissociation decreases as the temperature decreases. This makes HEPES a more effective buffering agent for maintaining enzyme structure and function at low temperatures. Lepe-Zuniga et al. reported a phototoxicity of HEPES when exposed to ambient light by the production of hydrogen peroxide, which is not a problem in bicarbonate-based cell culture buffers. It is therefore strongly advised to keep HEPES-containing solutions in darkness as much as possible.
HEPES has the following characteristics:

4-羟乙基哌嗪乙磺酸基本信息

中文名称 4-羟乙基哌嗪乙磺酸 英文名称 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid
中文别名

4-(2-羟乙基)-1-哌嗪基]乙磺酸; N-2-羟乙基哌嗪-N'-2-乙磺酸(HEPES); 4-(2-羟乙基)-1-哌嗪乙磺酸; N-(2-羟乙基)哌嗪-N’-2-乙烷磺酸; N-(2-羟乙基)哌嗪-N'-2-乙烷磺酸; 羟乙基哌嗪乙磺酸; N-2-羟乙基哌嗪-N'-2-乙磺酸;

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英文别名

hepesfreeacid; HEPES.1/2Na; GOOD'S BUFFER; HEPES; HEPES BUFFER PH 8.0; HEPES,1M solution; EIT hydrobromide; hepes solution;

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CAS号 7365-45-9 分子式 C8H18N2O4S
分子量 238.30500 精确质量 238.09900
PSA 89.46000 LOGP -0.55930

4-羟乙基哌嗪乙磺酸编号系统

MDL号 MFCD00006158

4-羟乙基哌嗪乙磺酸物化性质

外观与性状:
白色结晶粉末
密度:
1.07 g/mL at 20 °C
熔点:
234-238 °C
折射率:
n20/D 1.339
水溶解性:
Soluble
稳定性:
Stable. Combustible. Incompatible with strong oxidizing agents. Protect from moisture.
储存条件:
2-8ºC

安全信息

RTECS号:
TL6809000
安全说明:
S24/25-S22-S36-S26
WGK Germany:
1
危险类别码:
R36/37/38
海关编码:
29335995
危险品标志:
Xi

生产方法及用途

用途

本品是一种氢离子缓冲剂,能较长时间控制恒定的pH范围。

SDS 1.0 中文 展开
SDS 1.0 英文 展开
MSDS 中文 展开
1H NMR : Predict展开

核磁图谱 1H NMR : Predict

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国家名称 海关编码 海关数据更新时间 操作
中国 29335995 2019-03 申报要素
4-羟乙基哌嗪乙磺酸
CAS号:7365-45-9 分子式:C8H18N2O4S 分子量:238.30500

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