|Other names||3-amino-2,5-dichlorobenzoic acid|
|Identified uses||For industry use only. Chloramben is used as a herbicide to control grasses and broadleaf weeds on soybeans, dry beans, lima beans, asparagus, pumpkins, squash, corn, tomatoes, peppers, and sweet potatoes.|
|Uses advised against||no data available|
|Company||MOLBASE (Shanghai) Biotechnology Co., Ltd.|
|Address||Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road, |
Xuhui District, Shanghai, China
|Emergency phone number||+86-400-6021-666|
|Service hours||Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).|
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity – single exposure, Category 3
Carcinogenicity, Category 1B2.2 GHS label elements, including precautionary statements
|Signal word|| |
|Hazard statement(s)|| |
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H350 May cause cancer
P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P313 If skin irritation occurs: Get medical advice/attention.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313 If eye irritation persists: Get medical advice/attention.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P312 Call a POISON CENTER/doctor/…if you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/ attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to ...
none3.Composition/information on ingredients 3.1 Substances
|Chemical name||Common names and synonyms||CAS number||EC number||Concentration|
Consult a physician. Show this safety data sheet to the doctor in attendance.If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.In case of skin contact
Wash off with soap and plenty of water. Consult a physician.In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.4.2 Most important symptoms/effects, acute and delayed
ACUTE/CHRONIC HAZARDS: This compound emits toxic fumes when heated to decomposition.4.3 Indication of immediate medical attention and special treatment needed, if necessary Absorption, Distribution and Excretion
... /STUDIES IN A LACTATING COW SHOWED THAT OVER/ A PERIOD OF 4 DAYS, DIETARY CHLORAMBEN (5 PPM IN DAILY RATION) WAS RAPIDLY EXCRETED IN URINE (88%) & FECES (5%). NO RESIDUES WERE DETECTED IN THE MILK. APPROX 18% OF CHLORAMBEN IN URINE WAS PRESENT AS UNKNOWN CONJUGATED MATERIAL.5.Fire-fighting measures 5.1 Extinguishing media Suitable extinguishing media
Fires involving this material can be controlled using a dry chemical, carbon dioxide or Halon extinguisher.5.2 Specific hazards arising from the chemical
Flash point data for this compound is not available, but it is probably combustible.5.3 Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.6.Accidental release measures 6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.7.Handling and storage 7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 184.108.40.206 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.8.Exposure controls/personal protection 8.1 Control parameters Occupational Exposure limit values
no data availableBiological limit values
no data available8.2 Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.8.3 Individual protection measures, such as personal protective equipment (PPE) Eye/face protection
Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).Skin protection
Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.Respiratory protection
Wear dust mask when handling large quantities.Thermal hazards
no data available9.Physical and chemical properties
|Physical state||Purplish white powder or light purple solid.|
|Colour||COLORLESS CRYSTALLINE SOLID|
|Melting point/ freezing point||194-201ºC|
|Boiling point or initial boiling point and boiling range||373.2ºC at 760mmHg|
|Flammability||no data available|
|Lower and upper explosion limit / flammability limit||no data available|
|Auto-ignition temperature||no data available|
|Decomposition temperature||no data available|
|pH||no data available|
|Kinematic viscosity||no data available|
|Solubility||In water:700 mg/L (25 ºC)|
|Partition coefficient n-octanol/water (log value)||log Kow = 1.11|
|Vapour pressure||3.12E-06mmHg at 25°C|
|Density and/or relative density||1.607g/cm3|
|Relative vapour density||no data available|
|Particle characteristics||no data available|
no data available10.2 Chemical stability
RAPIDLY DECOMPOSED BY LIGHT10.3 Possibility of hazardous reactions
NonflammableCHLORAMBEN reacts with sodium hypochlorite solutions .10.4 Conditions to avoid
no data available10.5 Incompatible materials
no data available10.6 Hazardous decomposition products
DISASTER HAZARD: WHEN HEATED TO DECOMP, IT EMITS HIGHLY TOXIC FUMES SUCH AS /HYDROGEN/ CHLORIDE AND NITROUS OXIDES.11.Toxicological information Acute toxicity
- Oral: LD50 Rat oral 3,500 to 5,620 mg/kg
- Inhalation: no data available
- Dermal: no data available
no data availableSerious eye damage/irritation
no data availableRespiratory or skin sensitization
no data availableGerm cell mutagenicity
no data availableCarcinogenicity
no data availableReproductive toxicity
No information is available on the reproductive or developmental effects of chloramben in humans. Reduced ossification of skeletal bones was reported in the fetuses of rats orally exposed to chloramben.STOT-single exposure
no data availableSTOT-repeated exposure
no data availableAspiration hazard
no data available12.Ecological information 12.1 Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
STUDIES WITH SOIL MICROFLORA INDICATED THAT BREAKDOWN OF AMIBEN OCCURRED...& THAT THE CARBOXYL WAS CLEAVED SLOWLY BUT STEADILY.12.3 Bioaccumulative potential
Based on a measured water solubility of 700 mg/L at 25°C(2) and a regression derived equation(1), a BCF of 15.34 can be estimated for Amiben(SRC). This BCF value suggests that Amiben may not bioconcentrate in aquatic organisms(SRC).12.4 Mobility in soil
Amiben is expected to have anionic properties in most soil systems under environmental conditions (pH 5-9). When a column of Ella island soil type (pH 3.8, 1.6% organic matter, 82.7% sand, 12.2% silt, and 5.2% clay) was perfused for 160 days with a microbial medium containing 5.7 and 26.9 ppm (14)-COOH-labelled Amiben, 1.4 ppm (24.6%) and 5.0 ppm (18.5%) Amiben adsorbed to the soil, respectively. When a column of Kewaunee clay soil type (pH 6.4, 3.8% organic matter, 14% sand, 35.1% silt, and 48.7% clay) was perfused for 160 days with a microbial medium containing 5.7 and 26.9 ppm 14COOH-labelled Amiben, 0.6 ppm (11.1%) and 2.6 ppm (9.8%) Amiben adsorbed to the soil, respectively. When a column of Poygan silty clay soil type (pH 7.2, 10% organic matter, 6% sand, 58.9% silt, and 33.6% clay) was perfused for 160 days with a microbial medium containing 5.7 and 26.9 ppm 14COOH-labelled Amiben, 1.4 ppm (24.6%) and 5.4 ppm (20.1%) Amiben adsorbed to the soil, respectively. Therefore, soil pH and organic matter content are the primary factors controlling Amiben adsorption with higher adsorption to soil occurring either at a low pH with a low organic matter content or at a neutral pH with a high organic matter content(1).12.5 Other adverse effects
no data available13.Disposal considerations 13.1 Disposal methods Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.14.Transport information 14.1 UN Number
|ADR/RID: UN2588||IMDG: UN2588||IATA: UN2588|
|ADR/RID: PESTICIDE, SOLID, TOXIC, N.O.S.|
|IMDG: PESTICIDE, SOLID, TOXIC, N.O.S.|
|IATA: PESTICIDE, SOLID, TOXIC, N.O.S.|
|ADR/RID: 9||IMDG: 9||IATA: 9|
|ADR/RID: III||IMDG: III||IATA: III|
|ADR/RID: no||IMDG: no||IATA: no|
no data available14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
no data available15.Regulatory information 15.1 Safety, health and environmental regulations specific for the product in question
|Chemical name||Common names and synonyms||CAS number||EC number|
|European Inventory of Existing Commercial Chemical Substances (EINECS)||Listed.|
|United States Toxic Substances Control Act (TSCA) Inventory||Listed.|
|China Catalog of Hazardous chemicals 2015||Not Listed.|
|New Zealand Inventory of Chemicals (NZIoC)||Not Listed.|
|Philippines Inventory of Chemicals and Chemical Substances (PICCS)||Not Listed.|
|Vietnam National Chemical Inventory||Not Listed.|
|Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)||Not Listed.|
|Creation Date||Aug 12, 2017|
|Revision Date||Aug 12, 2017|
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/