108212-75-5 卡奇霉素 gamma1

卡奇霉素 gamma1

英文名称:calicheamicin γ1I
CAS:

108212-75-5

分子式:C55H74IN3O21S4
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卡奇霉素 gamma1简介

The calicheamicins are a class of enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora, with calicheamicin γ1 being the most notable. It was isolated originally in the mid-1980s from the chalky soil, or "calichi pits", located in Kerrville, Texas. The sample was collected by a scientist working for Lederle Labs. It is extremely toxic to all cells and, in 2000, a CD33 antigen-targeted immunoconjugate N-acetyl dimethyl hydrazide calicheamicin was developed and marketed as targeted therapy against the non-solid tumor cancer acute myeloid leukemia (AML). Calicheamicin γ1 and the related enediyne esperamicin are the two of the most potent antitumor agents known.

卡奇霉素 gamma1基本信息

中文名称 卡奇霉素 gamma1 英文名称 calicheamicin γ1I
中文别名

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英文别名

.calicheamicin γ1; calicheamicin γ1 I; .calichaemicin γ1; calicheamicin gamma1(I); Calicheamicin γ1I; Calicheamicin Gamma1; CALICHEAMICIN GAMMA(1)I;

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CAS号 108212-75-5 分子式 C55H74IN3O21S4
分子量 1368.35000 精确质量 1367.27000
PSA 409.64000 LOGP 4.36950
SDS 1.0 中文 展开
SDS 1.0 英文 展开
卡奇霉素 gamma1
CAS号:108212-75-5 分子式:C55H74IN3O21S4 分子量:1368.35000

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