113-78-0 去氨缩宫素

去氨缩宫素

英文名称:demoxytocin
CAS:

113-78-0

分子式:C43H65N11O12S2
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去氨缩宫素简介

Demoxytocin (INN) (brand names Sandopart, Odeax, Sandopral), also known as desaminooxytocin or deaminooxytocin, as well as 1-(3-mercaptopropanoic acid)oxytocin ([Mpa1]OT), is an oxytocic peptide drug and synthetic analogue of oxytocin that is marketed in several European countries, including Italy, Czechoslovakia, and Poland. It has the amino acid sequence Mpa-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Mpa = β-mercaptopropionic acid), and is an analogue of oxytocin wherein the leading cysteine is replaced with β-mercaptopropionic acid. Demoxytocin has similar activities as oxytocin, but is more potent and has a longer half-life in comparison. Unlike oxytocin, which is given via intravenous injection, demoxytocin is administered as a buccal tablet formulation. It is used to induce labor, promote lactation, and to prevent and treat puerperal (postpartum) mastitis (breast inflammation). The drug was first synthesized in 1960 and was introduced into clinical practice in 1971 by Sandoz.

去氨缩宫素基本信息

中文名称 去氨缩宫素 英文名称 demoxytocin
中文别名

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英文别名

desamino-oxytocin; deaminooxytocin; Deaminoxytocin;

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CAS号 113-78-0 分子式 C43H65N11O12S2
分子量 992.17300 精确质量 991.42600
PSA 424.11000 LOGP 1.91880

去氨缩宫素编号系统

EINECS号 204-034-9

去氨缩宫素物化性质

密度:
1.263g/cm3
沸点:
1518.8ºC at 760mmHg
闪点:
872.3ºC
折射率:
1.551
蒸汽压:
0mmHg at 25°C
SDS 1.0 中文 展开
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核磁图谱 1H NMR : Predict

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去氨缩宫素
CAS号:113-78-0 分子式:C43H65N11O12S2 分子量:992.17300

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