709-55-7 乙苯福林

乙苯福林

英文名称:3-[2-(Ethylamino)-1-hydroxyethyl]phenol
CAS:

709-55-7

分子式:C10H15NO2
  • 化合物简介
  • 基本信息
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  • 安全信息
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乙苯福林简介

Etilefrine is a cardiac stimulant used as an antihypotensive. It is a sympathomimetic amine of the 3-hydroxy-phenylethanolamine series used in treating orthostatic hypotension of neurological, cardiovascular, endocrine or metabolic origin. Intravenous infusion of this compound increases cardiac output, stroke volume, venous return and blood pressure in man and experimental animals, suggesting stimulation of both α and β adrenergic receptors. However, in vitro studies indicate that etilefrine has a much higher affinity for β1 (cardiac) than for β2 adrenoreceptors.
Intravenous etilefrine increases the pulse rate, cardiac output, stroke volume, central venous pressure and mean arterial pressure of healthy individuals. Peripheral vascular resistance falls during the infusion of 1–8mg etilefrine but begins to rise at higher dosage. Marked falls in pulse rate, cardiac output, stroke volume and peripheral bloodflow, accompanied by rises in mean arterial pressure, occur when etilefrine is infused after administration of intravenous propranolol 2,5mg. These findings indicate that etilefrine has both β1 and α1 adrenergic effects in man.

乙苯福林基本信息

中文名称 乙苯福林 英文名称 3-[2-(Ethylamino)-1-hydroxyethyl]phenol
中文别名

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英文别名

ethyl-chloro-phenyl-arsine; [3H]-(+/-)-Etilefrine; Arsinous chloride,ethylphenyl; ethylphenylarsine chloride; Aethylphenylarsinchlorid; 2-ethylamino-1-(3-hydroxy-phenyl)-ethanol; Arsine,chloroethylphenyl-(6CI,7CI,8CI); Chloroethylphenylarsine; Aethyl-phenyl-dithiocarbamidsaeure,Ammonium-Salz; ethyl(phenyl)arsinous chloride; Aethyl-chlor-phenyl-arsin; ammonium N-ethyl-N-phenyldithiocarbamate; (RS)-etilefrine; ethyl-phenyl-dithiocarbamic acid,ammonium salt; Aethyl-phenyl-chlor-arsin; ethylphenylephrine; Aethylphenylarsenchlorid; Ethylphenylchloroarsine;

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CAS号 709-55-7 分子式 C10H15NO2
分子量 181.23200 精确质量 181.11000
PSA 52.49000 LOGP 1.42600

乙苯福林编号系统

UNII ZB6F8MY53V

乙苯福林物化性质

密度:
1.127 g/cm3
沸点:
351.7ºC at 760 mmHg
闪点:
155.5ºC
折射率:
1.561

安全信息

海关编码:
2922509090
SDS 1.0 中文 展开
SDS 1.0 英文 展开
1H NMR : Predict展开

核磁图谱 1H NMR : Predict

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国家名称 海关编码 海关数据更新时间 操作
中国 2922509090 2019-03 申报要素
美国 2922505000 2019-03 概述
印度 29225090 2019-03 概述
欧盟 29225000 2019-03 概述
英国 2922500090 2019-03 概述
日本 292250000 2019-03 概述
韩国 2922509000 2019-03 概述
加拿大 2922500090 2019-03 概述
乙苯福林
CAS号:709-55-7 分子式:C10H15NO2 分子量:181.23200

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