188627-80-7 依菲巴特

依菲巴特

英文名称:eptifibatide
CAS:

188627-80-7

分子式:C35H49N11O9S2
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依菲巴特简介

Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class. Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of the arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.
Integrilin is sold in two strengths, globally: vials containing 2mg/ml (20mg totally) and 0.75mg/ml (75mg totally). A third size is sold in the US: 100 ml vials containing 2mg/ml (200mg totally).

依菲巴特基本信息

中文名称 依菲巴特 英文名称 eptifibatide
中文别名

依替巴肽; 埃替非巴肽; 依非巴肽;

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英文别名

Eptifibatide;

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CAS号 188627-80-7 分子式 C35H49N11O9S2
分子量 831.96200 精确质量 831.31600
PSA 374.49000 LOGP 1.62840

依菲巴特编号系统

UNII NA8320J834

依菲巴特物化性质

密度:
1.605 g/cm3
折射率:
1.735
SDS 1.0 中文 展开
SDS 1.0 英文 展开
依菲巴特
CAS号:188627-80-7 分子式:C35H49N11O9S2 分子量:831.96200

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