202189-78-4 比拉斯汀

比拉斯汀

英文名称:2-[4-[2-[4-[1-(2-ethoxyethyl)benzimidazol-2-yl]piperidin-1-yl]ethyl]phenyl]-2-methylpropanoic acid
CAS:

202189-78-4

分子式:C28H37N3O3
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  • 化合物简介
  • 基本信息
  • 物化性质
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比拉斯汀简介

Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).
It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.
Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.
Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.

比拉斯汀基本信息

中文名称 比拉斯汀 英文名称 2-[4-[2-[4-[1-(2-ethoxyethyl)benzimidazol-2-yl]piperidin-1-yl]ethyl]phenyl]-2-methylpropanoic acid
中文别名

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英文别名

Ilaxten; Bilastine; Bilaxten; Bilastine (INN); Bilatex; 2-[4-(2-{4-[1-(2-ethoxyethyl)-1h-benzimidazol-2-yl]piperidin-1-yl}ethyl)phenyl]-2-methylpropanoic acid;

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CAS号 202189-78-4 分子式 C28H37N3O3
分子量 463.61200 精确质量 463.28300
PSA 67.59000 LOGP 4.79500

比拉斯汀物化性质

密度:
1.16g/cm3
沸点:
639.1ºC at 760mmHg
闪点:
340.3ºC
折射率:
1.594
蒸汽压:
3.29E-17mmHg at 25°C
SDS 1.0 中文 展开
SDS 1.0 英文 展开
1H NMR : Predict展开

核磁图谱 1H NMR : Predict

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比拉斯汀
CAS号:202189-78-4 分子式:C28H37N3O3 分子量:463.61200

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