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春雷霉素

英文名称：Kasugamycin

化学药物杀虫剂杀细菌剂杀真菌剂

CAS :	6980-18-3	精确质量 :	379.15900
分子式 :	C14H25N3O9	logP :	-3.13710
分子量 :	379.36300	PSA :	218.81000

摩贝参考价：￥7711.00/kg我要纠正

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基本信息

纠错

中文名称：: 春雷霉素

中文别名：

(5-氨-3-甲基-6-(2,3,4,5,6-五羟基环已基氧化)吡喃-3-基)氨基-2-亚氨乙酸;

克死霉;

加收米;

春日霉素;

(5-氨基-2-甲基-6-(2,3,4,5,6-羟基环己基氧代)四氢吡喃-3-基)氨基-Α-亚氨醋酸;

英文名称：: Kasugamycin

英文别名：

[5-amino-2-methyl-6-(2,3,4,5,6-pentahydroxycyclohexyloxy)tetrahydropyran-3-yl]amino-α-iminoacetic acid;

kasumin-bordeaux;

KASUGAMYCIN HYDROCHLORIDE;

kasuminl;

Kasugamycin;

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CAS号：: 6980-18-3

分子式：: C14H25N3O9

分子量：: 379.36300

精确质量：: 379.15900

PSA：: 218.81000

物化性质

纠错

密度：: 1.973g/cm3

熔点：: 203ºC (dec)

沸点：: 585.944ºC at 760 mmHg

闪点：: 308.168ºC

折射率：: 1.738

储存条件：: 通风低温干燥

生产方法及用途

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生产方法

我国春雷霉素是一种小金色放线菌(Actinomycetes microaurous)所产生的代谢物。日本春日霉素是放线菌(Streptomyces kasugaensis)产生的代谢物。
1.砂土管菌种的制备将预先处理好的砂和土以3:2或2:1均匀混合,分装于玻璃试管中,加棉塞,外用纱布包扎,高压蒸汽灭菌后,选择孢子生长丰满的斜面菌种加无菌水制成孢子悬液于砂土管中,经干燥并封口,置于2～5℃的水箱内保存。
2.斜面孢子制备斜面培养在试管或茄形瓶中进行,加棉塞,高压蒸汽灭菌后,在无菌室用接种环沾取少许砂土孢子涂于斜面上,于28℃ 培养11～12d至表面孢子丰满,呈粉灰色或粉红色。 ...

用途

1.该品是农医两用抗菌素。春雷霉素对稻瘟病菌有强烈的抑制作用,用春雷霉素40μg/ml(每亩用量4g)喷雾,对苗瘟、叶瘟、穗颈瘟具有显著的治疗和保护用作,防治效果达70-85%,略优于或相当于600倍稻瘟净。与稻瘟净混用,可将防治效果提高到97%,还可延缓抗菌株的产生。低毒、内吸性杀菌剂。主要用于防治稻瘟病,在水稻抽穗期和灌浆期施药,通过内吸治疗作用发挥药效。防治稻瘟病用2%可湿性粉剂500～700倍液在发病初期施药,7～10d喷一次,叶瘟、穗颈瘟各2次。
2.对黄瓜炭疽病、高粱炭疽病、番茄叶霉病也有防治作用。使用时不能与碱性农药混用。

毒性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NM7521650

CHEMICAL NAME :: D-chiro-Inositol, 3-O-(2-amino-4-((carboxyiminomethyl)amino)-2,3,4,6-te tradeoxy- alpha-D-arabino-hexopyranosyl)-

CAS REGISTRY NUMBER :: 6980-18-3

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C14-H25-N3-O9

MOLECULAR WEIGHT :: 379.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 11400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SRTCAC Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. (Tohoku University, Research Institute for Tuberculosis and Cancer, 4-1 Seiryo-machi, Sendai, Japan) V.1- 1949- Volume(issue)/page/year: 36(1-4),10,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,515,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 21 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,515,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,515,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,515,1991